The CRO institute operate under the authority of the Italian Health Ministry for the clinical & experimental research functions. It practice excellence in clinical oncology, with particular emphasis on Onco-Hematology, Breast Surgery, Onco-Geriatrics, Pharmacogenetics/genomics and serve youth (14-19 years old). In addition, current research activity is based on five research lines:
- Tumor genetics and biology (basic and translational research)
- Tumor epidemiology and prevention
- Hematologic neoplasias. Translational and clinical research
- Solid tumors. Translational research to better diagnosis and treatment
- Infectious agents associated tumors
The Department of Translational Research, with laboratories area of about 4000 ms, CRO is equipped with state-of-art machinery for clinical and research activity, organized in Technology Platforms/Core Facilities.
Clinical research is based on mono- and multidisciplinary therapeutic protocols (conservative surgery in breast cancer, combined chemotherapy and radiotherapy in locally advanced, non small-cell lung cancer, interdisciplinary treatment of soft tissue sarcomas and ovarian tumors). Innovative protocols concern: Phase I-II studies of new drugs in metastatic tumors; therapeutic schemes specifically designed for elderly patients and patients with AIDS.
The CRO combines the hospital service and the scientific research with education.