Centro de Investigación Biomédica en Red, Bioingeniería, Biomateriales y Nanomedicina

The Biomedical Networking Research Center of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) is one of the 11 thematic areas of CIBER. CIBER groups some of the main Spanish research groups (more than 400) in biomedicine, located in more than 100 institutions distributed around Spain.

Av. Monforte de Lemos, 3-5. Pabellón 11. Planta 0 28029 Madrid
managed by CIBER-BBN


Increasing the number of sensors and actuators integrated in any flexible probes, such as thin-film probes, is an important objective in biomedical technology, and in particular in neurotechnology for the monitoring and control of neural activity with high spatial resolution.
The present invention relates to a flexible probe, where active elements are interconnected in order to implement a multiplexing technique, allowing to implement arrays with high aspect ratios, reducing the probe and connector footprints while integrating an increased number of active elements.


This innovative technology provides an alternative to the state of the art which covers the gaps found therein, by providing a flexible probe allowing to implement multiplexed active matrixes to increase the number of sensors and/or actuators in an active area of the probe with a high aspect ratio.
This flexible probe comprises a new way for the routing of the interconnection, which allow the implementation of epicortical neural probes with one or multiple strips as well as depth probes (such as DBS or intracortical probes) increasing their spatial resolution while improving their conformability with curved surfaces and/or minimizing their cross-section and footprint, therefore minimizing their invasiveness.


To be determined during further development.


Patient need addressed:
Neurological disorders


Readiness Level (TRL)

experimental proof of concept(The pie chart refers to the entire portfolio contained in the database of the helpdesk)

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Sample Buy from Wisdomain


Current status

EP Application


Available for

Licensing or Assignment


Rosa Villa, Xavier Illa, Anton Guimera, Ramon Garcia, Jose Antonio Garrido


Case manager: Aida Castellanos Paez

EU-Japan Centre
European CommissionMeti