-New method for supplying a functional liquid to biosensor micro-chambers in biosensor devices for multiple-analyte analysis.
-The amount of functional liquid supplied to each biosensor micro-chamber can be independently controlled and can flood at least one biosensor micro-chamber in a functional time period at an accurate very low flow rate by using the fluidic circuit.
-The flow of the functional liquid is selectively inlaid in the biosensor microchambers by one or more micro-valves controlled by an injection control unit so that the flow in each biosensor micro-chamber can be independently controlled with great accuracy.
-It is possible to multiplex a functional liquid to a plurality of biosensor micro-chambers accordingly to a pulsating flow mode.
-it is possible to supply within a functional time period each biosensor micro-chamber with an identical amount of functional liquid and the biosensor behaves as in the continuous flow mode with very low flow rate.
Competitive advantages: cost-effective device, that provide fast, simultaneous and real-time responses. A great reduction of the total flow of the functional liquid. Sensitive and accurate performance for multiple-analyte analysis that meet clinical requirements.
To be determined during further development
Patient need addressed: Multi-analyte detection for specific diseases
European patent application EP17382269.3 (May 12, 2017); International patent application PCT/EP2018/062230 (May 11, 2018)
Licensing or Assignment
INVENTOR / TEAM
Giacomo Saviozzi, Juan Pablo Salvador, Manuel Lopez de Miguel, Francisco Palacio, Raquel Pruna, Ma. Pilar Marco, Cecilia Laschi