TECHNOLOGY DESCRIPTION
This innovative method allows separation of nucleated fetal cells from maternal
peripheral blood at all gestational ages.
More specifically, the physiological separation of fetal cells allows the non invasive prenatal diagnosis and it is useful for subsequent chromosome, gene expression and protein investigations.
Prenatal diagnostic methods are a high unmet need for medical care. This innovative technology provides a method to isolate nucleated fetal cells, containing intact DNA, from the other cells present in maternal blood.
BENEFITS
- Isolation of nucleated fetal cells.
- Feasible at all gestational ages.
- Immuno-TAG not required.
LIMITATIONS
N.A.
APPLICATIONS
- Non invasive prenatal diagnosis.
- Method applicable for liquid biopsy diagnosis.
MATERIALS
Readiness Level (TRL)
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STATUS
Current status
US Patent
AVAILABILITY
Available for
Licensing
INVENTOR / TEAM
Debora Lattuada